Publications scientifiques gérées par la Biométrie

2024

• European journal of cancer : First-line real-world treatment patterns and survival outcomes in women younger or older than 40 years with metastatic breast cancer in the real-life multicenter French ESME cohort.
• International Journal of Environmental Research and Public Health : Consore: A Powerful Federated Data Mining Tool Driving a French Research Network to Accelerate Cancer Research.
• ESMO Open : Clinical characteristic and survival outcomes of patients with advanced NSCLC according to KRAS mutational status in the French real-life ESME cohort.
• Annals of Oncology : Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiotherapy in patients with locally advanced rectal cancer: long-term results of the UNICANCER-PRODIGE 23 trial.

2023

• Quality of Life Research : Flexible modeling of longitudinal health-related quality of life data accounting for informative dropout in a cancer clinical trial.
• BMC Medical Research Methodology : When a joint model should be preferred over a linear mixed model for analysis of longitudinal health-related quality of life data in cancer clinical trials.
• BMC Medicine : Association between progression-free survival and overall survival in women receiving first-line treatment for metastatic breast cancer: evidence from the ESME real-world database.
• European Journal of Cancer : Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER PRODIGE 23): Health-related quality of life longitudinal analysis.
• JAMA Network Open : Maintenance Therapy With Cetuximab After FOLFIRI Plus Cetuximab for RAS Wild-Type Metastatic Colorectal Cancer : A Phase 2 Randomized Clinical Trial.
• Cancers (Basel) : Time-Dependent ROC Curve Analysis for Assessing the Capability of Radiation-Induced CD8 T-Lymphocyte Apoptosis to Predict Late Toxicities after Adjuvant Radiotherapy of Breast Cancer Patients.

2022

• Quality of Life Research : Joint modelling with competing risks of dropout for longitudinal analysis of health-related quality of life in cancer clinical trials.
• Pharmaceutical Statistics : The importance of using ordinal scores for patient classification based on health-related quality of life trajectories.
• Cancer Radiotherapie : Clinical trials in Radiation Oncology : Methodologic approach.
• JAMA Oncology : Five-Year Outcomes of FOLFIRINOX vs Gemcitabine as Adjuvant Therapy for Pancreatic Cancer: A Randomized Clinical Trial.
• Cancers (Basel) : Development of a Clinical-Biological Model to Assess Tumor Progression in Metastatic Pancreatic Cancer: Post Hoc Analysis of the PRODIGE4/ACCORD11 Trial.

2021

• Quality of Life Research : Longitudinal analysis of health-related quality of life in cancer clinical trials: methods and interpretation of results.
• BMC Cancer : Optimal biological dose: a systematic review in cancer phase I clinical trials.
• The Lancet. Oncology :  Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy versus cytoreductive surgery alone for colorectal peritoneal metastases (PRODIGE 7): a multicentre, randomised, open-label, phase 3 trial.
• JCO Clinical Cancer Informatics : OSIRIS : A Minimum Data Set for Data Sharing and Interoperability in Oncology.
• Clinical Genitourinary Cancer :  Dose-Dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin With or Without Panitumumab in Patients With Advanced Urothelial Carcinoma: Multicenter, Randomized, French Unicancer GETUG/AFU 19 Study.
• The Lancet. Oncology : Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a multicentre, randomised, open-label, phase 3 trial.
• European Urology : Sunitinib Alone or After Nephrectomy for Patients with Metastatic Renal Cell Carcinoma: Is There Still a Role for Cytoreductive Nephrectomy?
• Computer Methods and Programs in Biomedicine : %TTD and %TUDD: New SAS macro programs to calculate the survival data of the time to deterioration for patient-reported outcomes data in oncology.

2020

• Statistical Methods in Medical Research : More accurate cancer-related excess mortality through correcting background mortality for extra variables.
• Quality of Life Research : Time to deterioration in cancer randomized clinical trials for patient-reported outcomes data: a systematic review.
• European Journal of Cancer : Guidelines for time-to-event end-point definitions in adjuvant randomised trials for patients with localised colon cancer: Results of the DATECAN initiative.
• BMC Medical Informatics and Decision Making : GUIP1: a R package for dose escalation strategies in phase I cancer clinical trials.
• Quality of Life Research : Longitudinal analysis of health-related quality of life in cancer clinical trials: methods and interpretation of results.
• BMC Medical Research Methodology : Handling informative dropout in longitudinal analysis of health-related quality of life: application of three approaches to data from the esophageal cancer clinical trial PRODIGE 5/ACCORD 17.
• Advanced Science (Weinh) : Machine Learning-Assisted Evaluation of Circulating DNA Quantitative Analysis for Cancer Screening.
• Thererapeutic Advances in Medical Oncology : Management and outcome of male metastatic breast cancer in the national multicenter observational research program Epidemiological Strategy and Medical Economics (ESME).

2019

• Health Informatics Journal : Reconciliation of patient/doctor vocabulary in a structured resource.
• Statistical Methods in Medical Research : More accurate cancer-related excess mortality through correcting background mortality for extra variables
• BMC Cancer : Health-related quality of life as an endpoint in oncology phase I trials: a systematic review.
• BMC Medical Research Methodology : Correcting for misclassification and selection effects in estimating net survival in clinical trials.
• JMIR Cancer : Complementary and Alternative Medicine in Patients With Breast Cancer: Exploratory Study of Social Network Forum Data.
• Quality of Life Research : Time to deterioration in cancer randomized clinical trials for patient-reported outcomes data: a systematic review.